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A Familial History of Pulmonary Fibrosis in Patients with Chronic Hypersensitivity Pneumonitis
Author(s) -
Tsukasa Okamoto,
Yasunari Miyazaki,
Makoto Tomita,
Meiyo Tamaoka,
Naohiko Inase
Publication year - 2012
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000338123
Subject(s) - medicine , hypersensitivity pneumonitis , pulmonary fibrosis , family history , bronchoalveolar lavage , genetic predisposition , pathogenesis , epidemiology , inhalation , lung , fibrosis , immunology , chronic cough , asthma , pathology , disease , anesthesia
Hypersensitivity pneumonitis (HP) is an immunologically mediated lung disease induced by the inhalation of a variety of antigens. Patients with chronic HP often have a family history of pulmonary fibrosis. This strongly suggests that both genetic and environmental factors play an important role in the pathogenesis of chronic HP.

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