The Most Negatively Charged Low-Density Lipoprotein L5 Induces Stress Pathways in Vascular Endothelial Cells | Zendy

ChingYi Chen | Zendy; HsiuChing Hsu | Zendy; AnSheng Lee | Zendy; Daming Tang | Zendy; LuPing Chow | Zendy; Chao-Yuh Yang | Zendy; Han Chen | Zendy; YuanTeh Lee | Zendy; ChuHuang Chen | Zendy

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The Most Negatively Charged Low-Density Lipoprotein L5 Induces Stress Pathways in Vascular Endothelial Cells

Author(s) -

ChingYi Chen,

HsiuChing Hsu,

AnSheng Lee,

Daming Tang,

LuPing Chow,

Chao-Yuh Yang,

Han Chen,

YuanTeh Lee,

ChuHuang Chen

Publication year - 2012

Publication title -

journal of vascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.58

H-Index - 74

eISSN - 1423-0135

pISSN - 1018-1172

DOI - 10.1159/000337463

Subject(s) - umbilical vein , endoplasmic reticulum , oxidative stress , apoptosis , chemistry , unfolded protein response , mitochondrion , microbiology and biotechnology , endocrinology , biology , medicine , biochemistry , in vitro

L5, the most negatively charged species of low-density lipoprotein (LDL), has been implicated in atherogenesis by inducing apoptosis of endothelial cells (ECs) and inhibiting the differentiation of endothelial progenitor cells. In this study, we compared the effects of LDL charge on cellular stress pathways leading to atherogenesis.

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