Cof a 1: Identification, Expression and Immunoreactivity of the First Coffee Allergen
Author(s) -
Nikolay Manavski,
Ulrike Peters,
Reinhold Brettschneider,
Marcus Oldenburg,
Xaver Baur,
Cordula Bittner
Publication year - 2012
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000337461
Subject(s) - allergen , green coffee , immunoglobulin e , coffea arabica , allergy , immunology , sensitization , chitinase , provocation test , complementary dna , biology , medicine , antibody , food science , gene , botany , biochemistry , alternative medicine , pathology
Over the past years, dust of green coffee beans has become known to be a relevant cause for occupational type I allergies. Up to now, allergy diagnostics is based on native green coffee bean extract which exhibits insufficient specificity due to interfering substances as well as batch-to-batch variations. No coffee allergen has been described on the molecular level so far. The aim of this study was to identify the first allergen of green coffee.
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