Acetaldehyde at a Low Concentration Synergistically Exacerbates Allergic Airway Inflammation as an Endocrine-Disrupting Chemical and as a Volatile Organic Compound | Zendy

Tetsuya Kawano | Zendy; Hiroto Matsuse | Zendy; Susumu Fukahori | Zendy; Tomoko Tsuchida | Zendy; Tomoya Nishino | Zendy; Chizu Fukushima | Zendy; Shigeru Kohno | Zendy

Open Access

Acetaldehyde at a Low Concentration Synergistically Exacerbates Allergic Airway Inflammation as an Endocrine-Disrupting Chemical and as a Volatile Organic Compound

Author(s) -

Tetsuya Kawano,

Hiroto Matsuse,

Susumu Fukahori,

Tomoko Tsuchida,

Tomoya Nishino,

Chizu Fukushima,

Shigeru Kohno

Publication year - 2012

Publication title -

respiration

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.264

H-Index - 81

eISSN - 1423-0356

pISSN - 0025-7931

DOI - 10.1159/000337112

Subject(s) - medicine , immunology , inflammation , ovalbumin , acetaldehyde , immunoglobulin e , allergic inflammation , endocrinology , chemistry , immune system , biochemistry , antibody , ethanol

Acetaldehyde is an endocrine-disrupting chemical (EDC) and a volatile organic compound (VOC). It is also a carcinogen and teratogen that causes bronchoconstriction in a subset of asthmatics. However, the mechanism through which acetaldehyde acts as an EDC/VOC causing allergic airway inflammation remains unknown.

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