Vascularization in Tissue Engineering: Angiogenesis versus Inosculation
Author(s) -
Matthias W. Laschke,
Michael D. Menger
Publication year - 2012
Publication title -
european surgical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.658
H-Index - 46
eISSN - 1421-9921
pISSN - 0014-312X
DOI - 10.1159/000336876
Subject(s) - angiogenesis , tissue engineering , neovascularization , blood vessel , regeneration (biology) , biomedical engineering , medicine , biology , microbiology and biotechnology
The key challenge in tissue engineering is the establishment of an efficient vascularization for tissue constructs guaranteeing long-term survival and function. Vascularization may be achieved by the stimulation of angiogenesis or the inosculation of preformed microvascular networks within the implants to the host microvasculature. The present review provides an overview of these two concepts applied in tissue engineering.
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