Effect of the Direct Renin Inhibitor Aliskiren in the Prevention of Experimental Contrast-Induced Nephropathy in the Rat | Zendy

Alla Eldeen Kedrah | Zendy; Elif Arı | Zendy; Yeşim Özen Alahdab | Zendy; Cuma Bülent Gül | Zendy; Beyza Macunluoğlu | Zendy; Aydın Atakan | Zendy; Ebru Aşıcıoğlu | Zendy; Fulya Çakalağaoğlu | Zendy; Mehmet Koç | Zendy

Open Access

Effect of the Direct Renin Inhibitor Aliskiren in the Prevention of Experimental Contrast-Induced Nephropathy in the Rat

Author(s) -

Alla Eldeen Kedrah,

Elif Arı,

Yeşim Özen Alahdab,

Cuma Bülent Gül,

Beyza Macunluoğlu,

Aydın Atakan,

Ebru Aşıcıoğlu,

Fulya Çakalağaoğlu,

Mehmet Koç

Publication year - 2012

Publication title -

kidney and blood pressure research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.806

H-Index - 51

eISSN - 1423-0143

pISSN - 1420-4096

DOI - 10.1159/000336104

Subject(s) - aliskiren , renin inhibitor , medicine , endocrinology , renal function , creatinine , renin–angiotensin system , nephropathy , kidney , contrast induced nephropathy , chemistry , diabetes mellitus , blood pressure

Renal vasoconstriction, activated by the renin-angiotensin system, plays a pivotal role in the pathogenesis of contrast-induced nephropathy (CIN). The purpose of this study was to evaluate the effect of aliskiren, a direct renin inhibitor, for the prophylaxis of experimental CIN in the rat.

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