Purple Sweet Potato Pigments Scavenge ROS, Reduce p53 and Modulate Bcl-2/Bax to Inhibit Irradiation-induced Apoptosis in Murine Thymocytes | Zendy

Yantao Han | Zendy; Xuehong Chen | Zendy; Jing Xie | Zendy; Song-Mei Zhan | Zendy; Chunbo Wang | Zendy; Lexin Wang | Zendy

Open Access

Purple Sweet Potato Pigments Scavenge ROS, Reduce p53 and Modulate Bcl-2/Bax to Inhibit Irradiation-induced Apoptosis in Murine Thymocytes

Author(s) -

Yantao Han,

Xuehong Chen,

Jing Xie,

Song-Mei Zhan,

Chunbo Wang,

Lexin Wang

Publication year - 2011

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000335801

Subject(s) - apoptosis , reactive oxygen species , viability assay , dichlorofluorescein , pigment , oxidative stress , chemistry , caspase 3 , microbiology and biotechnology , caspase , mtt assay , programmed cell death , western blot , biology , biochemistry , organic chemistry , gene

Purple sweet potato (PSP) pigments were proved to protect murine thymocytes from (60)Co γ-ray-induced mitochondria-mediated apoptosis in our previous study. In this study, we further investigated the effect of PSP pigments on apoptosis related ROS, p53 and Bcl-2 family.

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