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Maternal Serum Placental Growth Factor in Prospective Screening for Aneuploidies at 8–13 Weeks’ Gestation
Author(s) -
Pranav Pandya,
D. Wright,
Argyro Syngelaki,
Ranjit Akolekar,
K. H. Nicolaides
Publication year - 2012
Publication title -
fetal diagnosis and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.976
H-Index - 60
eISSN - 1421-9964
pISSN - 1015-3837
DOI - 10.1159/000335684
Subject(s) - medicine , trisomy , gestation , obstetrics , gestational age , human chorionic gonadotropin , aneuploidy , placental growth factor , fetus , pregnancy associated plasma protein a , gynecology , pregnancy , prospective cohort study , population , down syndrome , first trimester , biology , biochemistry , genetics , environmental health , hormone , gene , chromosome , psychiatry , vascular endothelial growth factor , vegf receptors
To investigate whether measurement of maternal serum placental growth factor (PLGF) can improve the performance of first-trimester combined screening for trisomy-21 by fetal nuchal translucency (NT) thickness and serum free β-human chorionic gonadotropin (β-hCG) and PAPP-A.

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