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Replication of the SH2B1 rs7498665 Association with Obesity in a Belgian Study Population
Author(s) -
Sigri Beckers,
Doreen Zegers,
Luc F. Van Gaal,
Wim Van Hul
Publication year - 2011
Publication title -
obesity facts
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.398
H-Index - 45
eISSN - 1662-4033
pISSN - 1662-4025
DOI - 10.1159/000335305
Subject(s) - medicine , obesity , logistic regression , population , single nucleotide polymorphism , genetic association , locus (genetics) , genome wide association study , demography , minor allele frequency , allele , genetics , genotype , gene , biology , environmental health , sociology
SH2B1 has been identified as an interesting candidate gene for complex obesity through genome-wide association studies. Therefore, we set out to replicate the reported association with rs7498665 in our Belgian study population and to extend our study with an additional tagSNP for the SH2B1 gene region.

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