Is Metformin Indicated as Primary Ovulation Induction Agent in Women with PCOS? A Systematic Review and Meta-Analysis | Zendy

T.I. Siebert | Zendy; Margarida Viola | Zendy; D. W. Steyn | Zendy; T. F. Kruger | Zendy

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Is Metformin Indicated as Primary Ovulation Induction Agent in Women with PCOS? A Systematic Review and Meta-Analysis

Author(s) -

T.I. Siebert,

Margarida Viola,

D. W. Steyn,

T. F. Kruger

Publication year - 2012

Publication title -

gynecologic and obstetric investigation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.631

H-Index - 63

eISSN - 1423-002X

pISSN - 0378-7346

DOI - 10.1159/000335253

Subject(s) - ovulation , medicine , ovulation induction , live birth , pregnancy , meta analysis , polycystic ovary , gynecology , metformin , obstetrics , pregnancy rate , randomized controlled trial , prospective cohort study , endocrinology , hormone , biology , diabetes mellitus , insulin resistance , genetics

A recent meta-analysis has proven that metformin (M) is highly effective for ovulation induction in the clomiphene citrate (CC)-resistant patient. There is uncertainty whether M should be introduced as a primary ovulation induction agent in polycystic ovarian syndrome (PCOS).

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