Combined Gene and Protein Expression of Hormone-Sensitive Lipase and Adipose Triglyceride Lipase, Mitochondrial Content, and Adipocyte Size in Subcutaneous and Visceral Adipose Tissue of Morbidly Obese Men | Zendy

Hélène De Naeyer | Zendy; D. Margriet Ouwens | Zendy; Yves Van Nieuwenhove | Zendy; Piet Pattyn | Zendy; Leen M. ‘t Hart | Zendy; JeanMarc Kaufman | Zendy; Henrike Sell | Zendy; Jürgen Eckel | Zendy; Claude Cuvelier | Zendy; Youri Taes | Zendy; Johannes Ruige | Zendy

Open Access

Combined Gene and Protein Expression of Hormone-Sensitive Lipase and Adipose Triglyceride Lipase, Mitochondrial Content, and Adipocyte Size in Subcutaneous and Visceral Adipose Tissue of Morbidly Obese Men

Author(s) -

Hélène De Naeyer,

D. Margriet Ouwens,

Yves Van Nieuwenhove,

Piet Pattyn,

Leen M. ‘t Hart,

JeanMarc Kaufman,

Henrike Sell,

Jürgen Eckel,

Claude Cuvelier,

Youri Taes,

Johannes Ruige

Publication year - 2011

Publication title -

obesity facts

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.398

H-Index - 45

eISSN - 1662-4033

pISSN - 1662-4025

DOI - 10.1159/000333445

Subject(s) - adipose triglyceride lipase , medicine , endocrinology , lipotoxicity , adipose tissue , adipocyte , hormone sensitive lipase , lipolysis , triglyceride , fatty liver , lipoprotein lipase , lipid droplet , perilipin , obesity , insulin resistance , cholesterol , disease

Lipotoxicity in obesity might be a failure of adipocytes to respond sufficiently adequate to persistent energy surplus. To evaluate the role of lipolytic enzymes or mitochondria in lipotoxicity, we studied expression levels of genes and proteins involved in lipolysis and mitochondrial DNA (mtDNA) content.

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