z-logo
open-access-imgOpen Access
Clinical, Physiological and Anti-Inflammatory Effect of Montelukast in Patients with Cough Variant Asthma
Author(s) -
Masaya Takemura,
Akio Niimi,
Hisako Matsumoto,
Tetsuya Ueda,
Hirofumi Matsuoka,
Masafumi Yamaguchi,
Makiko Jinnai,
Kazuo Chin,
Michiaki Mishima
Publication year - 2011
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000332835
Subject(s) - medicine , montelukast , methacholine , asthma , eosinophil , leukotriene , bronchial hyperresponsiveness , sputum , leukotriene d4 , visual analogue scale , anesthesia , spirometry , salmeterol , gastroenterology , leukotriene receptor , bronchodilator , respiratory disease , lung , pathology , tuberculosis
Cough variant asthma (CVA) is a phenotype of asthma presenting solely with coughing, characterized by airway hyperresponsiveness, eosinophilic inflammation and a cough response to bronchodilators. Leukotriene receptor antagonists (LTRAs) are antiasthma medications with anti-inflammatory and bronchodilatory properties. Although LTRAs exert antitussive effects in CVA, the mechanisms involved are unknown.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom