Apoptosis and Expression of the Bcl-2 Family of Proteins and P53 in Human Pancreatic Ductal Adenocarcinoma
Author(s) -
Dong Chen,
Xuefeng Zheng,
Dalu Kang,
Bomin Yan,
Xiaoyi Liu,
Yuan Gao,
Kejun Zhang
Publication year - 2011
Publication title -
medical principles and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 45
eISSN - 1423-0151
pISSN - 1011-7571
DOI - 10.1159/000332423
Subject(s) - tunel assay , apoptosis , immunohistochemistry , terminal deoxynucleotidyl transferase , bcl xl , bcl 2 associated x protein , pancreatic ductal adenocarcinoma , blot , cancer research , adenocarcinoma , medicine , bcl 2 family , in situ nick end labeling , pathology , biology , programmed cell death , pancreatic cancer , cancer , caspase 3 , gene , genetics
The purpose of this study was to clarify the association between P53 and the Bcl-2 family (Bcl-2, Bax, Bcl-xL, Bcl-xS) expression and apoptosis in pancreatic ductal adenocarcinoma (PDAC).
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