High Cholesterol Feeding May Induce Tubular Dysfunction Resulting in Hypomagnesemia
Author(s) -
Vanessa F. Favaro,
Fabíola M. Oshiro-Monreal,
Ana Carolina de Bragança,
Lúcia Andrade,
Antonio Carlos Seguro,
Claudia M.B. Helou
Publication year - 2011
Publication title -
kidney and blood pressure research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.806
H-Index - 51
eISSN - 1423-0143
pISSN - 1420-4096
DOI - 10.1159/000332399
Subject(s) - hypomagnesemia , endocrinology , medicine , distal convoluted tubule , chemistry , homeostasis , cotransporter , reabsorption , kidney , sodium , magnesium , organic chemistry
Hypomagnesemia may induce hypercholesterolemia, but the contrary has not been described yet. Thus, magnesium homeostasis was evaluated in rats fed a cholesterol-enriched diet for 8 days. This study has a relevant clinical application if hypomagnesemia, due to hypercholesterolemia, is confirmed in patients with long-term hypercholesterolemia.
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