Open AccessAssessing the Impact of Non-Differential Genotyping Errors on Rare Variant Tests of Association
Author(s) -
Scott Powers,
Shyam Gopalakrishnan,
Nathan Tintle
Publication year - 2011
Publication title -
human heredity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 62
eISSN - 1423-0062
pISSN - 0001-5652
DOI - 10.1159/000332222
Subject(s) - genotyping , heterozygote advantage , genotype , genetics , type i and type ii errors , allele , sample size determination , minor allele frequency , biology , statistics , allele frequency , mathematics , gene
We aim to quantify the effect of non-differential genotyping errors on the power of rare variant tests and identify those situations when genotyping errors are most harmful.
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