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How Individual Can Personalized Antiretroviral Treatment Be? Deep Salvage in an HIV-1-Infected Patient
Author(s) -
BjörnErik Ole Jensen,
Stefan Eßer,
Rolf Kaiser,
Nadine Luebke,
Dieter Häussinger
Publication year - 2012
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000332020
Subject(s) - regimen , human immunodeficiency virus (hiv) , antiretroviral therapy , antiretroviral treatment , salvage therapy , medicine , virology , drug resistance , viral load , antiretroviral drug , intensive care medicine , biology , chemotherapy , genetics
We present an HIV-1-infected male (who is now 52 years old) with a multi-drug-resistant virus and discuss the considerations finally leading to an antiretroviral regimen resulting in long-term viral suppression and excellent immunological response in a deep salvage situation. Even in a desperate situation with high-level multi-class resistance, highly individual, personalized antiretroviral regimes can be tailor-made to achieve unexpected improvements in the health status of a patient.

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