Amoxapine Inhibits Delayed Outward Rectifier K+ Currents in Cerebellar Granule Cells via Dopamine Receptor and Protein Kinase A Activation | Zendy

Guang Yang | Zendy; Menghua Zhou | Zendy; Zhen Ren | Zendy; Jiajie Xu | Zendy; YanAi Mei | Zendy

Open Access

Amoxapine Inhibits Delayed Outward Rectifier K<sup>+</sup> Currents in Cerebellar Granule Cells via Dopamine Receptor and Protein Kinase A Activation

Author(s) -

Guang Yang,

Menghua Zhou,

Zhen Ren,

Jiajie Xu,

YanAi Mei

Publication year - 2011

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000331725

Subject(s) - receptor , protein kinase a , dopamine receptor d2 , phosphorylation , chemistry , microbiology and biotechnology , patch clamp , dopamine receptor , endocrinology , medicine , biology , biochemistry

Although tricyclic antidepressants amoxapine is proposed to target 5-HT and D2 receptors, very few studies have addressed the effect of amoxapine on molecular and cellular mechanisms via receptor pathways. In this study, we test the effect of amoxapine on rat cerebellar granule neurons (CGNs) to address this possibility.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research