Upregulation of MicroRNA-210 Regulates Renal Angiogenesis Mediated by Activation of VEGF Signaling Pathway under Ischemia/Perfusion Injury in vivo and in vitro | Zendy

Yong Li | Zendy; Yuanlei Lou | Zendy; Jue Wu | Zendy; Qiongfang Ruan | Zendy; An Xie | Zendy; Fei Guo | Zendy; Cui Su-ping | Zendy; Zhifeng Deng | Zendy; Yang Wang | Zendy

Open Access

Upregulation of MicroRNA-210 Regulates Renal Angiogenesis Mediated by Activation of VEGF Signaling Pathway under Ischemia/Perfusion Injury in vivo and in vitro

Author(s) -

Yong Li,

Yuanlei Lou,

Jue Wu,

Qiongfang Ruan,

An Xie,

Fei Guo,

Cui Su-ping,

Zhifeng Deng,

Yang Wang

Publication year - 2011

Publication title -

kidney and blood pressure research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.806

H-Index - 51

eISSN - 1423-0143

pISSN - 1420-4096

DOI - 10.1159/000331054

Subject(s) - angiogenesis , downregulation and upregulation , renal ischemia , microrna , cd31 , matrigel , biology , ischemia , vascular endothelial growth factor , neovascularization , cancer research , microbiology and biotechnology , reperfusion injury , medicine , vegf receptors , gene , biochemistry

MicroRNAs (miRNAs) are endogenous, non-coding, small RNAs that regulate gene expression and function, but little is known about regulation of miRNAs in the kidneys under normal or pathologic conditions. Here, we sought to investigate the potential involvement of miRNAs in renal ischemia/reperfusion (I/R) injury and angiogenesis and to define some of the miRNAs possibly associated with renal angiogenesis.

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