Open AccessEffects of Hydrogen Sulfide Synthesis Inhibitors on Posthypoxic Ventilatory Behavior in the C57BL/6J Mouse
Author(s) -
Lucas M. Donovan,
Michael W. Moore,
Carl B. Gillombardo,
Sam Chai,
Kingman P. Strohl
Publication year - 2011
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000330722
Subject(s) - medicine , saline , respiratory system , hypoxia (environmental) , anesthesia , endocrinology , oxygen , chemistry , organic chemistry
H(2)S synthesis inhibitors (HSSI) have been shown to impact respiratory control. For instance, the HSSI hydroxylamine (HA) decreases the respiratory discharge rate from isolated medullary sections, and HA in addition to other HSSIs propargylglycine and amino-oxyacetic acid (AOAA) have been found to reduce hypoxic responsiveness.
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