Antiproteinuric Effect of Chemokine C-C Motif Ligand 2 Inhibition in Subjects with Acute Proliferative Lupus Nephritis
Author(s) -
Alessandro Blè,
Marta Mosca,
Giorgio Di Loreto,
Angelo Guglielmotti,
Giuseppe Biondi,
Stefano Bombardieri,
Giuseppe Remuzzi,
Piero Ruggenenti
Publication year - 2011
Publication title -
american journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 85
eISSN - 1421-9670
pISSN - 0250-8095
DOI - 10.1159/000330685
Subject(s) - medicine , lupus nephritis , albuminuria , gastroenterology , renal function , urinary system , proteinuria , urology , chemokine , immunology , endocrinology , kidney , inflammation , disease
To test the role of chemokine C-C motif ligand 2 (CCL2) in the pathogenesis of lupus nephritis (LN), we evaluated the effects of CCL2 inhibition by bindarit therapy in patients with systemic lupus and active renal disease.
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