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Cortical and Hippocampal Atrophy in Patients with Autosomal Dominant Familial Alzheimer’s Disease
Author(s) -
Liana G. Apostolova,
Kristy Hwang,
Luis D. Medina,
Amity E. Green,
Meredith N. Braskie,
Rebecca A. Dutton,
Jeffrey Lai,
Daniel H. Geschwind,
Jeffrey L. Cummings,
Paul M. Thompson,
John M. Ringman
Publication year - 2011
Publication title -
dementia and geriatric cognitive disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.026
H-Index - 110
eISSN - 1421-9824
pISSN - 1420-8008
DOI - 10.1159/000330471
Subject(s) - atrophy , hippocampal formation , dementia , psen1 , degenerative disease , alzheimer's disease , neuroscience , psychology , pathology , central nervous system disease , medicine , disease , presenilin
Both familial and sporadic Alzheimer's disease (AD) result in progressive cortical and subcortical atrophy. Familial autosomal dominant AD (FAD) allows us to study AD brain changes presymptomatically.

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