Degradation of Filamin Induces Contraction of Vascular Smooth Muscle Cells in Type-I Collagen Matrix Honeycombs | Zendy

Masashi Uchida | Zendy; Itsuko Ishii | Zendy; Kaori Hirata | Zendy; Fumiko Yamamoto | Zendy; Kaori Tashiro | Zendy; Takayoshi Suzuki | Zendy; Yuji Nakayama | Zendy; Noritaka Ariyoshi | Zendy; Mitsukazu Kitada | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Degradation of Filamin Induces Contraction of Vascular Smooth Muscle Cells in Type-I Collagen Matrix Honeycombs

Author(s) -

Masashi Uchida,

Itsuko Ishii,

Kaori Hirata,

Fumiko Yamamoto,

Kaori Tashiro,

Takayoshi Suzuki,

Yuji Nakayama,

Noritaka Ariyoshi,

Mitsukazu Kitada

Publication year - 2011

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000330076

Subject(s) - filamin , actin , flna , cytoskeleton , microbiology and biotechnology , cytoplasm , contraction (grammar) , biophysics , biology , cell , biochemistry , endocrinology

Dedifferentiated rabbit vascular smooth muscle cells (SMCs) exhibit similar features to differentiated SMCs when cultured in three-dimensional matrices of type-I collagen called "honeycombs," but the mechanism is unknown. The role of filamin, an actin-binding protein that links actin filaments in SMCs, was investigated.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research