Caffeic Acid Phenethyl Ester Inhibits Proliferation and Migration, and Induces Apoptosis in Platelet-Derived Growth Factor-BB-Stimulated Human Coronary Smooth Muscle Cells | Zendy

Hung Chin Ho | Zendy; Ho Ching Chang | Zendy; Chih Tai Ting | Zendy; ChanYen Kuo | Zendy; Vivian C. Yang | Zendy

Open Access

Caffeic Acid Phenethyl Ester Inhibits Proliferation and Migration, and Induces Apoptosis in Platelet-Derived Growth Factor-BB-Stimulated Human Coronary Smooth Muscle Cells

Author(s) -

Hung Chin Ho,

Ho Ching Chang,

Chih Tai Ting,

ChanYen Kuo,

Vivian C. Yang

Publication year - 2011

Publication title -

journal of vascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.58

H-Index - 74

eISSN - 1423-0135

pISSN - 1018-1172

DOI - 10.1159/000329819

Subject(s) - apoptosis , caffeic acid phenethyl ester , chemistry , microbiology and biotechnology , growth factor , smooth muscle , vascular smooth muscle , platelet derived growth factor , cell growth , myocyte , platelet , caffeic acid , platelet derived growth factor receptor , biochemistry , endocrinology , medicine , biology , receptor , antioxidant

Restenosis after a percutaneous coronary intervention (PCI) during treatment for coronary artery disease is closely related to smooth muscle cell (SMC) proliferation and migration. In this study, we investigated the effects of caffeic acid phenethyl ester (CAPE) and its underlying mechanism on human coronary SMCs (HCSMCs) after platelet-derived growth factor-BB (PDGF-BB) stimulation in vitro.

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