Findings on Preoperative Brain MRI Predict Histopathology in Children with Cerebellar Neoplasms | Zendy

Jonathan A. Forbes | Zendy; Adam S. Reig | Zendy; Jason G. Smith | Zendy; Walter J. Jermakowicz | Zendy; Luke Tomycz | Zendy; Sheila Shay | Zendy; David Sun | Zendy; Curtis A. Wushensky | Zendy; Matthew M. Pearson | Zendy

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Findings on Preoperative Brain MRI Predict Histopathology in Children with Cerebellar Neoplasms

Author(s) -

Jonathan A. Forbes,

Adam S. Reig,

Jason G. Smith,

Walter J. Jermakowicz,

Luke Tomycz,

Sheila Shay,

David Sun,

Curtis A. Wushensky,

Matthew M. Pearson

Publication year - 2011

Publication title -

pediatric neurosurgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.385

H-Index - 72

eISSN - 1423-0305

pISSN - 1016-2291

DOI - 10.1159/000329627

Subject(s) - histopathology , medicine , medulloblastoma , pilocytic astrocytoma , ependymoma , radiology , pathology , nuclear medicine , astrocytoma , glioma , cancer research

The majority of pediatric patients with cerebellar neoplasms harbor pilocytic astrocytomas (PAs), medulloblastomas, or ependymomas. Knowledge of a preoperative likelihood of histopathology in this group of patients has the potential to influence many aspects of care. Previous studies have demonstrated hyperintensity on diffusion-weighted imaging to correlate with medulloblastomas. Recently, measurement of T(2)-weighted signal intensity (T2SI) was shown to be useful in identification of low-grade cerebellar neoplasms. The goal of this study was to assess whether objective findings on these MRI sequences reliably correlated with the underlying histopathology.

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