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Acute Silicoproteinosis: Therapy Success
Author(s) -
Demet Karnak,
Gözde Köycü Buhari,
Esra Erdemlı,
Serpil Dızbay Sak,
Yusuf Kağan Kadıoğlu
Publication year - 2011
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000329563
Subject(s) - medicine , dlco , bronchoalveolar lavage , nuclear medicine , lung , surgery , diffusing capacity , lung function
2 : 53 mm Hg) and decreased lung diffusion capacity (DLCO: 62% of predicted) were ob-served. The bronchoalveolar lavage fluid had a milky ap-pearance. Transbronchial biopsy detected granular, eo-sinophilic, lipoproteinaceous material filling airspaces ( fig. 1 b). The industrial material, to which he had been exposed, was composed of fibrous material, identified as mainly silicon carbide on spectrometric analysis and X- A 39-year-old male with a 3-pack-year smoking his-tory presented with exertional dyspnea for 1 month. He had been working in an iron-steel factory for 10 years and had been cleaning a dusty storage for the past 3 weeks. He had been given antibiotics for fever and had cyanosis upon admission. Computed tomography revealed bibasi-lar ground-glass opacities ( fig. 1 a). Laboratory analyses were normal except for high serum lipid/triglyceride lev-

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