Inactivation of COX-2, HMLH1 and CDKN2A Gene by Promoter Methylation in Gastric Cancer: Relationship with Histological Subtype, Tumor Location and Helicobacter pylori Genotype | Zendy

Markênia Kélia Santos Alves | Zendy; Adriana Camargo Ferrasi | Zendy; Marcos Antônio Pereira de Lima | Zendy; Márcia Valéria Pitombeira Ferreira | Zendy; Maria Inês de Moura Campos Pardini | Zendy; Sílvia Helena Barem Rabenhorst | Zendy

Open Access

Inactivation of COX-2, HMLH1 and CDKN2A Gene by Promoter Methylation in Gastric Cancer: Relationship with Histological Subtype, Tumor Location and Helicobacter pylori Genotype

Author(s) -

Markênia Kélia Santos Alves,

Adriana Camargo Ferrasi,

Marcos Antônio Pereira de Lima,

Márcia Valéria Pitombeira Ferreira,

Maria Inês de Moura Campos Pardini,

Sílvia Helena Barem Rabenhorst

Publication year - 2011

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000329475

Subject(s) - methylation , dna methylation , microbiology and biotechnology , promoter , cdkn2a , biology , gene , gene expression , genetics

We aimed to evaluate the inactivation of COX-2, HMLH1 and CDKN2A by promoter methylation and its relationship with the infection by different Helicobacter pylori strains in gastric cancer.

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