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Toll-Like Receptor 9 Is a Novel Biomarker for Esophageal Squamous Cell Dysplasia and Squamous Cell Carcinoma Progression
Author(s) -
Heikki Takala,
Joonas H. Kauppila,
Ylermi Soini,
Katri S. Selander,
Katri Vuopala,
Petri Lehenkari,
Juha Saarnio,
Tuomo J. Karttunen
Publication year - 2011
Publication title -
journal of innate immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.078
H-Index - 64
eISSN - 1662-8128
pISSN - 1662-811X
DOI - 10.1159/000329115
Subject(s) - pathology , dysplasia , epithelium , immunohistochemistry , tlr9 , esophageal cancer , squamous carcinoma , cancer research , esophagus , medicine , carcinoma , biology , cancer , gene expression , biochemistry , dna methylation , gene
Stimulation of Toll-like receptor 9 (TLR9) has been linked to invasion in various cancer cells in vitro. We investigated TLR9 expression in normal, dysplastic and malignant esophageal squamous epithelium.

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