Open AccessMechanisms of Renal Cell Apoptosis Induced by Cyclosporine A: A Systematic Review of in vitro Studies
Author(s) -
Zheng Xiao,
Chengwen Li,
Juan Shan,
Lei Luo,
Li Feng,
Jun Lu,
Shengfu Li,
Dan Long,
Youping Li
Publication year - 2011
Publication title -
american journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 85
eISSN - 1421-9670
pISSN - 0250-8095
DOI - 10.1159/000328584
Subject(s) - apoptosis , medicine , fadd , oxidative stress , nephrotoxicity , downregulation and upregulation , viability assay , in vitro , caspase 3 , pharmacology , cancer research , caspase , programmed cell death , immunology , kidney , biology , biochemistry , gene
Chronic cyclosporine A (CsA) nephrotoxicity (CCN) is a major cause of chronic renal dysfunction and has no effective clinical interventions yet.
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