Open AccessMeta-Analysis of Homogeneous Subgroups Reveals Association between <i>PDE4D</i> Gene Variants and Ischemic Stroke
Author(s) -
Dankyu Yoon,
Sue K. Park,
Daehee Kang,
Taesung Park,
Ji Wan Park
Publication year - 2011
Publication title -
neuroepidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.217
H-Index - 87
eISSN - 1423-0208
pISSN - 0251-5350
DOI - 10.1159/000327915
Subject(s) - meta analysis , medicine , single nucleotide polymorphism , allele , genotype , odds ratio , stroke (engine) , genetic association , snp , genetics , gene , biology , mechanical engineering , engineering
An Icelandic study showed a significant positive association between phosphodiesterase 4D (PDE4D) gene variants and stroke. However, subsequent studies reported conflicting results, possibly due to small sample sizes and the heterogeneity of the studies.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom