Effects of Dialysate Glucose Concentration on Heart Rate Variability in Chronic Hemodialysis Patients: Results of a Prospective Randomized Trial | Zendy

Manuela Ferrario | Zendy; Jochen G. Raimann | Zendy; Stephan Thijssen | Zendy; M.G. Signorini | Zendy; Anja Kruse | Zendy; José A. Díaz-Buxó | Zendy; S. Cerutti | Zendy; Nathan W. Levin | Zendy; Peter Kotanko | Zendy

Open Access

Effects of Dialysate Glucose Concentration on Heart Rate Variability in Chronic Hemodialysis Patients: Results of a Prospective Randomized Trial

Author(s) -

Manuela Ferrario,

Jochen G. Raimann,

Stephan Thijssen,

M.G. Signorini,

Anja Kruse,

José A. Díaz-Buxó,

S. Cerutti,

Nathan W. Levin,

Peter Kotanko

Publication year - 2011

Publication title -

kidney and blood pressure research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.806

H-Index - 51

eISSN - 1423-0143

pISSN - 1420-4096

DOI - 10.1159/000327851

Subject(s) - medicine , heart rate variability , diabetes mellitus , heart rate , randomized controlled trial , autonomic nervous system , hemodialysis , endocrinology , prospective cohort study , insulin , cardiology , blood pressure

Chronic hemodialysis (HD) patients suffer from an appallingly high cardiovascular mortality. During HD, patients are exposed to dialysate glucose, which may alter blood glucose levels and thus exert effects on the autonomic nervous system. Heart rate variability (HRV) is an established indicator of autonomic nervous system activity and a predictor of cardiovascular outcomes. This study investigated the effects of two commonly used dialysate glucose concentrations [100 mg/dl (HD100), and 200 mg/dl (HD200)] on HRV in chronic HD patients.

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