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Induction of Thymic Stromal Lymphopoietin Production by Xylene and Exacerbation of Picryl Chloride-Induced Allergic Inflammation in Mice
Author(s) -
Nozomi Satou,
Kenji Ishihara,
Masahiro Hiratsuka,
Hiroyuki Tanaka,
Yasuo Endo,
Saburô Saitô,
Yoichiro Iwakura,
Warren J. Leonard,
Noriyasu Hirasawa
Publication year - 2011
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000327545
Subject(s) - thymic stromal lymphopoietin , picryl chloride , inflammation , chemistry , immunology , xylene , knockout mouse , tumor necrosis factor alpha , oxazolone , receptor , immune system , medicine , biochemistry , toluene , organic chemistry
Some chemical compounds in the environment worsen allergic inflammation. In this study, we examined whether organic solvents induce the production of thymic stromal lymphopoietin (TSLP) which elicits Th2-type immune responses.

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