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Cholinergic Hyperresponsiveness of Peripheral Lung Parenchyma in Chronic Obstructive Pulmonary Disease
Author(s) -
Tatiana Lanças,
David I. Kasahara,
Jefferson Luiz Gross,
Ruy Camargo Pires-Neto,
Daniel Deheinzelin,
Thaís Mauad,
Elnara Márcia Negri,
Marisa Dolhnikoff
Publication year - 2011
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000326897
Subject(s) - medicine , copd , eosinophil , parenchyma , airway resistance , acetylcholine , pathology , lung , bronchial hyperresponsiveness , cd8 , immunology , respiratory disease , asthma , immune system
Up to 60% of chronic obstructive pulmonary disease (COPD) patients can present airway hyperresponsiveness. However, it is not known whether the peripheral lung tissue also shows an exaggerated response to agonists in COPD.

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