Hypoxia Induces Tumor Aggressiveness and the Expansion of CD133-Positive Cells in a Hypoxia-Inducible Factor-1α-Dependent Manner in Pancreatic Cancer Cells | Zendy

Okito Hashimoto | Zendy; Kazuya Shimizu | Zendy; Shuho Semba | Zendy; Sachie Chiba | Zendy; Yonson Ku | Zendy; Hiroshi Yokozaki | Zendy; Yuichi Hori | Zendy

Open Access

Hypoxia Induces Tumor Aggressiveness and the Expansion of CD133-Positive Cells in a Hypoxia-Inducible Factor-1α-Dependent Manner in Pancreatic Cancer Cells

Author(s) -

Okito Hashimoto,

Kazuya Shimizu,

Shuho Semba,

Sachie Chiba,

Yonson Ku,

Hiroshi Yokozaki,

Yuichi Hori

Publication year - 2011

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000325538

Subject(s) - hypoxia (environmental) , metastasis , pancreatic cancer , cancer research , cancer cell , cxcr4 , transfection , biology , cancer stem cell , cell culture , tumor hypoxia , cancer , stem cell , immunology , chemistry , medicine , chemokine , microbiology and biotechnology , immune system , radiation therapy , genetics , organic chemistry , oxygen

Intratumoral hypoxia is known to lead to increased aggressiveness and distant metastasis. However, the interplay underlying these actions is still unknown.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research