Adenosine Activates AMPK to Phosphorylate Bcl-XL Responsible for Mitochondrial Damage and DIABLO Release in HuH-7 Cells | Zendy

Donqin Yang | Zendy; Takahiro Yaguchi | Zendy; Takashi Nakano | Zendy; Tomoyuki Nishizaki | Zendy

Open Access

Adenosine Activates AMPK to Phosphorylate Bcl-X<sub>L</sub> Responsible for Mitochondrial Damage and DIABLO Release in HuH-7 Cells

Author(s) -

Donqin Yang,

Takahiro Yaguchi,

Takashi Nakano,

Tomoyuki Nishizaki

Publication year - 2011

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000325207

Subject(s) - ampk , microbiology and biotechnology , protein kinase a , phosphorylation , small interfering rna , adenosine , amp activated protein kinase , apoptosis , tfam , transfection , chemistry , activator (genetics) , mitochondrion , biology , biochemistry , mitochondrial biogenesis , gene

Accumulating evidence has pointed to AMP-activated protein kinase (AMPK) as an inducer of apoptosis in a variety of cancer cells. The present study aimed at understanding AMPK signals for adenosine-induced HuH-7 cell apoptosis.

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