Uric Acid and Pentraxin-3 Levels Are Independently Associated with Coronary Artery Disease Risk in Patients with Stage 2 and 3 Kidney Disease | Zendy

Mehmet Kanbay | Zendy; Mustafa İkizek | Zendy; Yalçın Solak | Zendy; Yusuf Selçoki | Zendy; Sema Uysal | Zendy; Ferah Armutçu | Zendy; Beyhan Eryonucu | Zendy; Adrian Covic | Zendy; Richard J. Johnson | Zendy

Open Access

Uric Acid and Pentraxin-3 Levels Are Independently Associated with Coronary Artery Disease Risk in Patients with Stage 2 and 3 Kidney Disease

Author(s) -

Mehmet Kanbay,

Mustafa İkizek,

Yalçın Solak,

Yusuf Selçoki,

Sema Uysal,

Ferah Armutçu,

Beyhan Eryonucu,

Adrian Covic,

Richard J. Johnson

Publication year - 2011

Publication title -

american journal of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 85

eISSN - 1421-9670

pISSN - 0250-8095

DOI - 10.1159/000324916

Subject(s) - medicine , uric acid , disease , kidney disease , coronary artery disease , cardiology , risk factor , stage (stratigraphy) , paleontology , biology

Cardiovascular disease is prevalent in chronic kidney disease (CKD). Uric acid is increased in subjects with CKD and has been linked with cardiovascular mortality in this population. However, no study has evaluated the relationship of uric acid with angiographically proven coronary artery disease (CAD) in this population. We therefore investigated the link between serum uric acid (SUA) levels and (i) extent of CAD assessed by the Gensini score and (ii) inflammatory parameters, including C-reactive protein (CRP) and pentraxin-3, in patients with mild-to-moderate CKD.

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