Programming of Adult Cardiovascular Disease following Exposure to Late-Gestation Hyperglycemia
Author(s) -
MELISSA M. AGOUDEMOS,
Benjamin E. Reinking,
Stacia L. Koppenhafer,
Jeffrey L. Segar,
Thomas Scholz
Publication year - 2011
Publication title -
neonatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.399
H-Index - 84
eISSN - 1661-7819
pISSN - 1661-7800
DOI - 10.1159/000324863
Subject(s) - medicine , offspring , endocrinology , gestation , pregnancy , diabetes mellitus , in utero , diastole , cardiac function curve , ischemia , fetus , biology , heart failure , blood pressure , genetics
In utero exposure to hyperglycemia is becoming increasingly prevalent as the number of women entering pregnancy with type II diabetes, or developing gestational diabetes, increases. Both animal studies and epidemiologic investigations have found cardiovascular abnormalities in adult offspring of hyperglycemic mothers (OHM).
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