In vitro and in vivo Effects of Metformin on Human Adipose Tissue Adiponectin
Author(s) -
Alessandra Zulian,
Raffaella Cancello,
Andrea Girola,
Luisa Gilardini,
Luisella Alberti,
Marina Croci,
Giancarlo Micheletto,
Piergiorgio Danelli,
Cecilia Invitti
Publication year - 2011
Publication title -
obesity facts
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.398
H-Index - 45
eISSN - 1662-4033
pISSN - 1662-4025
DOI - 10.1159/000324582
Subject(s) - adiponectin , metformin , adipose tissue , in vivo , medicine , endocrinology , adipokine , inflammation , diabetes mellitus , insulin resistance , biology , microbiology and biotechnology
The effects of metformin on adiponectin production are controversial and have never been investigated in human adipose tissue. We analysed whether metformin modulates, in vitro and in vivo, gene expression, protein content, and secretion of adiponectin.
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