Proteomic Approach to the Study of Statin Pleiotropy in Kidney Transplant Patients | Zendy

Vanessa Pérez | Zendy; Maribel Navarro-Muñoz | Zendy; Sebastián Mas | Zendy; Beatriz Bayés | Zendy; Mari Cruz Pastor | Zendy; Eva MartínezCáceres | Zendy; Ricardo Lauzurica | Zendy; Jesús Egido | Zendy; R. Romero | Zendy

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Proteomic Approach to the Study of Statin Pleiotropy in Kidney Transplant Patients

Author(s) -

Vanessa Pérez,

Maribel Navarro-Muñoz,

Sebastián Mas,

Beatriz Bayés,

Mari Cruz Pastor,

Eva MartínezCáceres,

Ricardo Lauzurica,

Jesús Egido,

R. Romero

Publication year - 2011

Publication title -

pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.51

H-Index - 59

eISSN - 1423-0313

pISSN - 0031-7012

DOI - 10.1159/000324311

Subject(s) - atorvastatin , medicine , dyslipidemia , inflammation , pleiotropy , renal function , pharmacology , kidney , endocrinology , gastroenterology , obesity , chemistry , biochemistry , gene , phenotype

Statins are prescribed in kidney transplant recipients in order to manage dyslipidemia, a common complication in these patients. The efficacy of statins in reducing cholesterol levels has been accompanied by pleiotropic effects. Fifty-four kidney transplant patients were included in the present study, the objective of which was to ascertain the effect of 12 weeks of atorvastatin therapy (10 mg/day) on the patients' lipid profile, renal function, markers of inflammation and plasma peptide profile.

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