A Modified in vivo Flow Variation Technique of Microdialysis for Sampling Uremic Toxins in the Subcutaneous Interstitial Compartment
Author(s) -
Leonard Ebah,
Paul Brenchley,
Beatrice Coupes,
Sandip Mitra
Publication year - 2011
Publication title -
blood purification
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 57
eISSN - 1421-9735
pISSN - 0253-5068
DOI - 10.1159/000324207
Subject(s) - microdialysis , interstitial fluid , uremia , chemistry , urea , extracellular fluid , in vivo , dextran , dialysis , analyte , chromatography , medicine , extracellular , biochemistry , biology , microbiology and biotechnology
Uremic toxins are typically measured in plasma and little is known of their interstitial concentrations. We undertook experiments to validate a microdialysis technique for simultaneous recovery of small and large uremic toxins in the subcutaneous interstitial fluid (ISF).
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