Altered Expression of Myogenic Regulatory Factors in the Mouse Model of Amyotrophic Lateral Sclerosis | Zendy

Raquel Manzano | Zendy; Janne M. Toivonen | Zendy; Sara Oliván | Zendy; Ana Cristina Calvo | Zendy; María MorenoIgoa | Zendy; Marı́a Jesús Muñoz | Zendy; P. Zaragoza | Zendy; Alberto GarcíaRedondo | Zendy; Rosario Osta | Zendy

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Altered Expression of Myogenic Regulatory Factors in the Mouse Model of Amyotrophic Lateral Sclerosis

Author(s) -

Raquel Manzano,

Janne M. Toivonen,

Sara Oliván,

Ana Cristina Calvo,

María MorenoIgoa,

Marı́a Jesús Muñoz,

P. Zaragoza,

Alberto GarcíaRedondo,

Rosario Osta

Publication year - 2011

Publication title -

neurodegenerative diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.98

H-Index - 57

eISSN - 1660-2862

pISSN - 1660-2854

DOI - 10.1159/000324159

Subject(s) - myf5 , myogenin , myod , amyotrophic lateral sclerosis , skeletal muscle , sod1 , endocrinology , medicine , myogenic regulatory factors , denervation , biology , chemistry , myogenesis , disease

In the superoxide dismutase 1 (SOD1)-G93A mouse model of amyotrophic lateral sclerosis (ALS), skeletal muscle is a key target of mutant SOD1 toxicity. However, the expression of factors that control the regenerative potential of the muscle is unknown in this model.

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