Anti-inflammatory Profile of FTO Gene Expression in Adipose Tissues From Morbidly Obese Women
Author(s) -
Ximena Terra,
Teresa Auguet,
José Antonio Porras,
Yunuen Quintero,
Carmen Aguilar,
Anna Luna,
Merc eacute Hern aacute ndez,
Fàtima Sabench,
Daniel Del Castillo,
Crist oacute bal Richart
Publication year - 2010
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000323979
Subject(s) - adipose tissue , adiponectin , medicine , endocrinology , adipokine , insulin resistance , leptin , obesity
The fat mass and obesity associated (FTO) gene has been found to contribute to the risk of obesity in humans, but the function and regulation of FTO mRNA expression in adipose tissues remain to be clarified. Our aims were to assess the FTO gene expression in subcutaneous and visceral adipose tissues from morbidly obese women and its relation with obesity, insulin resistance indices, and most importantly, to obesity-related inflammatory markers.
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