Extent of Liver Resection for Hilar Cholangiocarcinoma (Klatskin Tumor): How Much Is Enough? | Zendy

Thomas M. van Gulik | Zendy; Anthony T. Ruys | Zendy; O. Busch | Zendy; Erik A. Rauws | Zendy; Dirk J. Gouma | Zendy

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Extent of Liver Resection for Hilar Cholangiocarcinoma (Klatskin Tumor): How Much Is Enough?

Author(s) -

Thomas M. van Gulik,

Anthony T. Ruys,

O. Busch,

Erik A. Rauws,

Dirk J. Gouma

Publication year - 2011

Publication title -

digestive surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.762

H-Index - 69

eISSN - 1421-9983

pISSN - 0253-4886

DOI - 10.1159/000323825

Subject(s) - medicine , surgery , resection , liver function , hepatectomy , biliary drainage , mortality rate , klatskin tumor , survival rate , gastroenterology

Hilar resection in combination with extended liver resections has resulted in a higher rate of R0 resections and increased survival in patients with hilar cholangiocarcinoma (HCCA). This aggressive surgical approach is, however, associated with high rates of operative morbidity and mortality, largely due to postresectional liver failure. We previously reported a series after resection of HCCA in which R0 resection rate was 59% with a mortality rate of 10%. In this study, we assessed mortality of extended liver resections after optimizing liver functional reserve and application of parenchyma-sparing techniques.

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