Expression of DcR3 and Its Effects in Kaposi’s Sarcoma-Associated Herpesvirus-Infected Human Endothelial Cells | Zendy

SeungMin Yoo | Zendy; JaeHyuk Jang | Zendy; Sil Kim | Zendy; Haewol Cho | Zendy; MyungShin Lee | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Expression of DcR3 and Its Effects in Kaposi’s Sarcoma-Associated Herpesvirus-Infected Human Endothelial Cells

Author(s) -

SeungMin Yoo,

JaeHyuk Jang,

Sil Kim,

Haewol Cho,

MyungShin Lee

Publication year - 2011

Publication title -

intervirology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.641

H-Index - 61

eISSN - 1423-0100

pISSN - 0300-5526

DOI - 10.1159/000323522

Subject(s) - virology , apoptosis , biology , umbilical vein , antibody , virus , immunology , cancer research , in vitro , biochemistry

Kaposi's sarcoma-associated herpesvirus (KSHV) is classified as a gamma-herpesvirus and it causes Kaposi's sarcoma in patients infected with the human immunodeficiency virus (HIV). Decoy receptor 3 (DcR3) is known as a decoy receptor for Fas ligand, LIGHT and TL1A and it can neutralize the biological effect of TL1A by inhibiting the TL1A-DR3 interaction in human endothelial cells. The present study examined the expression of DcR3 in human endothelial cells and its effect during the early stages of KSHV infection.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research