Open AccessAntiviral Resistance Mutations and Genotype-Associated Amino Acid Substitutions in Treatment-Naïve Hepatitis B Virus-Infected Individuals from the Indian Subcontinent
Author(s) -
Ashrafali Mohamed Ismail,
Prasanna Samuel,
C.E. Eapen,
Rajesh Kannangai,
Priya Abraham
Publication year - 2011
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000323521
Subject(s) - adefovir , hepatitis b virus , entecavir , virology , genotype , lamivudine , biology , hepatitis b , genbank , gene , mutation , virus , genetics
Antiviral resistance is a major challenge to the treatment currently available for hepatitis B virus (HBV). In this study, mutations that may affect the antiviral efficacy in treatment-naïve HBV-infected individuals were analyzed.
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