Microvascular Endothelial Dysfunction in Obstructive Sleep Apnea Is Caused by Oxidative Stress and Improved by Continuous Positive Airway Pressure Therapy
Author(s) -
Nikolaus Büchner,
Ivo Quack,
Magdalena Woznowski,
Constanze Stähle,
Ulrich Wenzel,
Lars Christian Rump
Publication year - 2011
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000323266
Subject(s) - medicine , continuous positive airway pressure , endothelial dysfunction , obstructive sleep apnea , oxidative stress , vasodilation , endothelium , endocrinology , cardiology , sodium nitroprusside , anesthesia , nitric oxide
Endothelial dysfunction has recently been demonstrated in obstructive sleep apnea (OSA), but the underlying mechanisms are not entirely understood. Oxidative stress is a typical feature of OSA.
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