Patterns of Inflammatory Responses in Large and Small Airways in Smokers with and without Chronic Obstructive Pulmonary Disease | Zendy

Sergejs Isajevs | Zendy; Immanuels Taivāns | Zendy; Darja Svirina | Zendy; Gunta Strazda | Zendy; Uldis Kopeika | Zendy

Open Access

Patterns of Inflammatory Responses in Large and Small Airways in Smokers with and without Chronic Obstructive Pulmonary Disease

Author(s) -

Sergejs Isajevs,

Immanuels Taivāns,

Darja Svirina,

Gunta Strazda,

Uldis Kopeika

Publication year - 2011

Publication title -

respiration

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.264

H-Index - 81

eISSN - 1423-0356

pISSN - 0025-7931

DOI - 10.1159/000322560

Subject(s) - medicine , copd , lung , inflammation , airway , cd8 , airway obstruction , histone deacetylase 2 , pulmonary function testing , pathology , immunology , immune system , surgery , histone , histone deacetylase , biochemistry , chemistry , gene

Chronic obstructive pulmonary disease (COPD) is characterised by progressive and irreversible airway obstruction. Smoking causes persistent inflammation in lung tissue. However, differences in inflammatory responses between the large and small airways have not been systematically explored among smokers with and without COPD.

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