Predicting Nocturnal Hypoventilation in Hypercapnic Chronic Obstructive Pulmonary Disease Patients Undergoing Long-Term Oxygen Therapy
Author(s) -
Julia Tárrega,
Antonio Antón,
Rosa Güell,
Mercedes Mayos,
Daniel Samolski,
Sergi Martí,
Eva Farrero,
Enric Prats Gil,
J. Sanchís
Publication year - 2010
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000321372
Subject(s) - medicine , copd , hypoventilation , dlco , hypercapnia , oxygen therapy , hypoxemia , arterial blood , anesthesia , obesity hypoventilation syndrome , pulmonary function testing , cardiology , diffusing capacity , obstructive sleep apnea , respiratory system , lung , lung function
Chronic obstructive pulmonary disease (COPD) patients are very sensitive to changes in pulmonary mechanics and central ventilation control during sleep and may develop significant gas exchange alterations with increased hypoxemia and hypercapnia. Oxygen therapy improves nocturnal desaturation but can worsen hypoventilation.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom