Liver Regeneration in Surgical Animal Models – A Historical Perspective and Clinical Implications | Zendy

Kim Erlend Mortensen | Zendy; Arthur Revhaug | Zendy

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Liver Regeneration in Surgical Animal Models – A Historical Perspective and Clinical Implications

Author(s) -

Kim Erlend Mortensen,

Arthur Revhaug

Publication year - 2010

Publication title -

european surgical research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.658

H-Index - 46

eISSN - 1421-9921

pISSN - 0014-312X

DOI - 10.1159/000321361

Subject(s) - regeneration (biology) , liver regeneration , medicine , liver transplantation , perioperative , medline , liver failure , animal model , general surgery , surgery , transplantation , biology , biochemistry , microbiology and biotechnology

METHODS/AIMS: Despite improved preoperative evaluation, surgical techniques and perioperative intensive care, some patients still experience postoperative liver failure in part due to insufficient regeneration. The aim of this review is to give the reader a historical synopsis of the major trends in animal research on liver regeneration from the early experiments in 1877 up to modern investigation. A major focus is placed on the translational value of experimental surgery.

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