Vascular Dysfunction in Streptozotocin-Induced Experimental Diabetes Strictly Depends on Insulin Deficiency | Zendy

Matthias Oelze | Zendy; Maike Knorr | Zendy; Swenja Schuhmacher | Zendy; Tjebo Heeren | Zendy; Christian F. Otto | Zendy; Eberhard Schulz | Zendy; Kurt Reifenberg | Zendy; Philip Wenzel | Zendy; Thomas Münzel | Zendy; Andreas Daiber | Zendy

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Vascular Dysfunction in Streptozotocin-Induced Experimental Diabetes Strictly Depends on Insulin Deficiency

Author(s) -

Matthias Oelze,

Maike Knorr,

Swenja Schuhmacher,

Tjebo Heeren,

Christian F. Otto,

Eberhard Schulz,

Kurt Reifenberg,

Philip Wenzel,

Thomas Münzel,

Andreas Daiber

Publication year - 2011

Publication title -

journal of vascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.58

H-Index - 74

eISSN - 1423-0135

pISSN - 1018-1172

DOI - 10.1159/000320627

Subject(s) - apocynin , medicine , diabetes mellitus , endocrinology , insulin , oxidative stress , streptozotocin , endothelial dysfunction , nadph oxidase , type 1 diabetes , nitric oxide synthase , nitric oxide

In previous studies we and others have shown that streptozotocin (STZ)-induced diabetes in rats is associated with vascular oxidative stress and dysfunction. In the present study, we sought to determine whether vascular dysfunction and oxidative stress strictly depend on insulin deficiency.

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