Aortic Adventitial Fibroblasts Participate in Angiotensin-Induced Vascular Wall Inflammation and Remodeling
Author(s) -
Brian Tieu,
Xiaoxi Ju,
Chang Lee,
Hong Sun,
Wanda S. LeJeune,
Adrián Recinos,
Allan R. Brasier,
Ronald G. Tilton
Publication year - 2010
Publication title -
journal of vascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 74
eISSN - 1423-0135
pISSN - 1018-1172
DOI - 10.1159/000320358
Subject(s) - fibroblast , angiotensin ii , monocyte , proinflammatory cytokine , inflammation , cytokine , biology , adventitia , chemokine , in vivo , in vitro , chemistry , microbiology and biotechnology , endocrinology , immunology , medicine , biochemistry , blood pressure
The role of adventitial fibroblasts in the vascular inflammation observed in the adventitia of large vessels in numerous cardiovascular diseases remains unclear. Our objective was to explore the contribution of these cells to angiotensin II (Ang II)-induced aortic inflammation and adventitial expansion.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom